Pattern of Aerobic Bacterial Pathogens Causing Wound Infection at a Tertiary Teaching Hospital in Bangladesh with Special Reference to Methicillin Resistant Staphylococcus aureus and Extended Spectrum Beta Lactamases

Background: Wound infection gaining utmost importance day by because of emergence drug resistant bacteria. Objective: This study was carried out to see the pattern aerobic bacterial pathogens along with MRSA and ESBL producing strains causing wound infection. Methodology: cross sectional conducted from May 2010 April 2011. swabs were taken patients suffering infections admitted in different surgical wards Rajshahi Medical College Hospital, Rajshahi, Bangladesh. The place department Microbiology College, General Surgery, Orthopedic Surgery Gynaecology & Obstetrics Rajshahi. Two samples collected each patient with, one for microscopy other culture. Gram staining culture swab done isolation identification Bacteria. Antimicrobial susceptibility testing isolates performed using modified Kirby-Bauer technique Mueller-Hinton agar commercially available antimicrobial discs manufactured Oxoid Diagnostic. Results: A total 300 collected. Culture yielded growth 175(58.33%) cases, which 138 (78.86%) gram negative. From negative bacteria 52(37.68%) positive they distributed as K. pneumoniae 05(55.56%), E. coli 35(54.68%), Pr. mirabilis 05(20.83%) Ps. aeruginosa 05(17.00%). All producers 100.0% against ampicillin, cotrimoxazole, ceftriaxone ceftazidime. Ciprofloxacin 80.0 88.6%, gentamicin 40.0 60.0%, aztreonam 60.0 netilmycin 20.0 60% resistant. co-trimoxazole cloxacillin. None showed resistance vancomycin. Conclusion: Drug are quite high among isolated most agent. Bangladesh Journal Infectious Diseases, June 2022;9(1):15-24